Figure 2. Overexpression of miR-542-3p suppressed the proliferation of osteosarcoma cells. (A) MTT assay showed that miR-542-3p mimics slowed down the growth of osteosarcoma cell line 143B and U-2OS, while miR-542-3p inhibitors enhanced it. **P<0.01 compared with NC or blank group; (B) Colony-forming growth assay, overexpression of miR-542-3p suppressed the proliferation of 143B and U-2OS cells, whereas low expressed miR-542-3p promoted it. *P<0.05, **P<0.01 compared with the NC group.