Research Paper Volume 11, Issue 2 pp 350—370

BCL2L10/BECN1 modulates hepatoma cells autophagy by regulating PI3K/AKT signaling pathway

Figure 3. The expression ofBCL2L10 was low in hepatocellular carcinoma (HCC) tissues and cells. (A) The expression of BCL2L10 mRNA in HCC detected by qRT-PCR. (B) The expression of BCL2L10 in L-02 normal liver cells and 3 groups of hepatoma cells detected by qRT-PCR. (C) Western Blot showed the low expression of BCL2L10 in HCC tissues. (D) Immunohistochemistry showed that the normal liver tissues had more brown granules than HCC tissues (× 40). * P<0.05). (E) The expression of BECN1 mRNA in L-02 normal liver cells and 3 groups of hepatoma cells detected by qRT-PCR. (F) The expression of BECN1 in L-02 normal liver cells and 3 groups of hepatoma cells detected by qRT-PCR. (G) Western Blot showed the low expression of BECN1 in HCC tissues.