Research Paper Volume 11, Issue 5 pp 1427—1439

FoxD2-AS1 promotes glioma progression by regulating miR-185-5P/HMGA2 axis and PI3K/AKT signaling pathway

Figure 6. The effect of FOXD2-AS1 on glioma growth in vivo. (A-D) The effect of FOXD2-AS1 on glioma growth in mice injected with U251 (A, C) or U87 cells (B, D) transfected with sh-FOXD2-AS1 or sh-NC. (E, F) The effect of FOXD2-AS1 knockdown on miR-185-5p expression in glioma tissues of mice injected with U251 and U87 cells was analyzed by qRT-PCR. *p < 0.05, **p < 0.01 vs. Control; #p < 0.05, ##p < 0.01 vs. NC. Control, non-transfected cells; sh-NC, cells transfected with shRNA-control.