Research Paper Volume 11, Issue 5 pp 1471—1485

LINC00702 suppresses proliferation and invasion in non-small cell lung cancer through regulating miR-510/PTEN axis

Figure 6. PTEN was a target gene of miR-510. (A) Western blot analysis of the expressions of PTEN, p-Akt and Akt in NSCLC cells co-transfected with pcDNA3.1-LINC00702 or/and miR-510 mimics. (B) Relative PTEN protein levels in NCI-H441 and PC-9 cells. (C) Relative p-Akt protein levels in NCI-H441 and PC-9 cells. (D) The expression of PTEN in NSCLC cells co-transfected with pcDNA3.1-LINC00702 or/and miR-510 mimics. (E) Relative PTEN expression were calculated. *P<0.05 and **P<0.01 were considered to indicate a statistically significant difference.