Research Paper Volume 11, Issue 5 pp 1564—1579

Running wheel access fails to resolve impaired sustainable health in mice feeding a high fat sucrose diet

Figure 1. Kaplan-Meier survival curves of the four different experimental groups; two low fat (LF) diet groups, one sedentary (LF (-)RW) and one exercise group (LF (+)RW); and two high fat (HFS) groups, one sedentary (HFS (-)RW) and one exercise group (HFS (+)RW). Samples sizes were LF (-)RW n=119, LF (+)RW n=109, HFS (-)RW n=118, and HFS (+)RW n=100. There was a significant reduction in survival in sedentary mice on an HFS diet compared to LF diet (p<0.001, log-rank test) and there was a significant reduction in survival in exercising mice on a HFS diet compared to LF diet (p<0.01, log-rank test). The table below the figure indicates the three different percentiles of the four different experimental groups, the 50% percentile is also indicated with the dotted line in the figure.