Research Paper Volume 11, Issue 5 pp 1564—1579

Running wheel access fails to resolve impaired sustainable health in mice feeding a high fat sucrose diet

Figure 2. (A) Body weight development measured over their life time and indicated every 1.5 months. There was a significant reduction of body weight in mice on a LF diet (p<0.001), in mice with access to a running wheel (p<0.001), and an increase in body weight with age (p<0.001). Data are averages from n=18-104 mice per group; ± SEM. (B) Average 3 or 6 months energy intake. Data are averages from n=18-104 mice per group; ± SEM *p<0.05 **p<0.01 ***p<0.001 per time point analysis (Bonferonni corrected) (C) Absorption efficiencies for the four experimental groups at the four different time points. Absorption efficiencies were higher in mice on HFS diet compared to mice on a LF diet. Data are averages from n=2-3 mice per group; ± SEM *p<0.05, **p<0.01 per time point analysis (Bonferonni corrected).