Research Paper Volume 11, Issue 9 pp 2583—2609

Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice

Figure 2. Assessment of bone structure, body composition, and cardiological analyses. (A-C) Bone mineral density (BMD) and body composition were examined by dual-energy X-ray absorptiometry (DEXA) (n=10). (A) Bone mineral density. (B) Fat percent. (C) Lean/fat ratio. (D-J) Heart dimensions and functions were assessed using an echocardiography (n=6-8). Dimensions of (D) left ventricular internal diameter in diastole, (E) left ventricular internal diameter in systole, (F) left ventricular posterior wall in diastole, and (G) left ventricular posterior wall in systole were determined. (H) Ejection fraction (%). (I) Fractional shortening. (J) E/e’ ratio. Data are represented as the mean ± SEM. *P < 0.05 and **P < 0.01 compared with the control group (t-test two tailed).