Research Paper Volume 11, Issue 9 pp 2653—2669

Prostate enlargement and altered urinary function are part of the aging process

Figure 1. Lower urinary tract measurements show age related changes. (A) Aging mice show a significant increase in total urine spots as well as an increase in smaller urine spots as measured by void spot assay. (B) Aging significantly increases bladder mass. (C) Aging significantly increases bladder volume as calculated from caliper measurements. (D) Age significantly increases anterior prostate (AP) mass. (E) Aging significantly increases ventral prostate (VP) mass. (F) Aging significantly increases dorsolateral prostate (DLP) mass. *, p-value < 0.05; ***, p-value < 0.001; ****, p-value < 0.0001.