Research Paper Volume 11, Issue 9 pp 2735—2748

RON and RONΔ160 promote gastric cancer cell proliferation, migration, and adaption to hypoxia via interaction with β-catenin

Figure 6. Impact of RON and β-catenin knockdown on KATOIII cell growth, survival and migration. (A) and (B) CCK-8 and colony formation assays showing the effects of RON and/or β-catenin knockdown using targeted siRNAs on KATOIII cell growth. (C) Flow cytometric analysis of apoptosis among KATOIII cells transfected with RON and/or β-catenin siRNAs. (D) Transwell assays showing effect of RON and/or β-catenin knockdown on KATOIII cell migration. Scale bar = 50 μm. ** p<0.01 vs Blank group.