Research Paper Volume 11, Issue 10 pp 3376—3391

MicroRNA-335/ID4 dysregulation predicts clinical outcome and facilitates leukemogenesis by activating PI3K/Akt signaling pathway in acute myeloid leukemia

Figure 2. Aberrant miR-335/ID4 expression predicted clinical outcome in AML. (A) The prognostic value of miR-335 expression for OS and LFS in non-M3-AML and CN-AML patients. (B) The prognostic value of ID4 expression for OS and LFS in non-M3-AML and CN-AML patients. (C) The prognostic value of ID4 expression for OS and LFS among CN-AML patients based on TCGA databases. (D) The prognostic value of ID4 expression for OS among CN-AML patients obtained by bioinformatics analysis. The effect of ID4 expression on prognosis was determined by the Genomicscape (http://genomicscape.com/microarray/survival.php). (E) The prognostic value of combined miR-335/ID4 expression for OS and LFS in non-M3-AML and CN-AML patients.