Research Paper Volume 11, Issue 12 pp 3969—3992

AGTR1 promotes lymph node metastasis in breast cancer by upregulating CXCR4/SDF-1α and inducing cell migration and invasion

Figure 1. AGTR1 expression is associated with lymph node metastasis. (A) Representative images of AGTR1 expression in lymph node-negative or -positive tissues by IHC. (B) HSCORE of AGTR1 protein expression in breast cancer tissues from lymph node-positive or lymph node-negative patients. *** P<0.001. (C) Relative amount of AGTR1 mRNA in cancer tissues from lymph node-positive or -negative patients in the Oncomine database. *** P<0.001.