Research Paper Volume 11, Issue 12 pp 4159—4182

Proteomics-based identification of different training adaptations of aged skeletal muscle following long-term high-intensity interval and moderate-intensity continuous training in aged rats

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Figure 2. Relative protein abundances in the red gastrocnemius muscle of rats in the MICT, HIIT, and SED groups. (A) Heat map and (B) volcano plot of significantly up- and downregulated proteins in the red gastrocnemius muscle from MICT and SED rats (p < 0.05, fold change > ± 1.5). (C) Heat map and (D) volcano plot of significantly up- and downregulated proteins in the red gastrocnemius muscle from HIIT and SED rats. (E) Overlap of proteins up- and downregulated following different modes of exercise training compared with their levels in the SED group.