Figure 2AB. . Transcriptome changes induced by TCQA, 1235 genes were significantly selected: 435 were upregulated and 800 downregulated. (A) Summary of the functional categories of upregulated genes in response to TCQA treatment. (B) Summary of the functional categories of downregulated genes in response to TCQA treatment. Analyses for the down and upregulated genes were performed individually using Database for Annotation, Visualization and Integrated Discovery v6.8 (DAVID). Bars represent the number of genes implicated in each category. *Statistically significant (P ≤0.01). **Statistically significant (P ≤0.001). ***Statistically significant (P ≤0.0001).