Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels

Yunsung Lee; Sanaa Choufani; Rosanna Weksberg; Samantha L. Wilson; Victor Yuan; Amber Burt; Carmen Marsit; Ake T. Lu; Beate Ritz; Jon Bohlin; Håkon K. Gjessing; Jennifer R. Harris; Per Magnus; Alexandra M. Binder; Wendy P. Robinson; Astanand Jugessur; Steve Horvath

doi:doi:10.18632/aging.102049

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Research Paper Volume 11, Issue 12 pp 4238—4253

Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels

Figure 2. Gestational age estimation of the RPC and Mayne et al. (2017)’s placental clock. (A) Scatter plot between observed GA and DNAm-predicted GA (RPC) across all trimesters. (B) Scatter plot between observed GA and DNAm-predicted GA (Mayne et al. 2017) across all trimesters. (C) Zoom-in on panel A restricting GA > 25 weeks. (D) Zoom-in on panel B restricting GA > 25 weeks.