Research Paper Volume 11, Issue 14 pp 5192—5205

Down-regulation of lncRNA MALAT1 alleviates vascular lesion and vascular remodeling of rats with hypertension

Figure 2. Expression of lncRNA MALAT1 and Notch-1 was elevated in vascular tissues of HTN rats. (A) expression of of lncRNA MALAT1 and Notch-1 in thoracic aorta vascular tissues detected by RT-qPCR; (B) protein band of Notch-1 in thoracic aorta vascular tissues; (C) expression of Notch-1 in thoracic aorta vascular tissues detected by western blot analysis; * P < 0.05 vs the Con group; # P < 0.05 vs the AngII + si-Con group; & P < 0.05 vs the AngII + DMSO group; n = 10, data were expressed as mean ± standard deviation; one-way ANOVA was used for analyzing data, pairwise comparison was analyzed by Tukey’s post hoc test.