Research Paper Volume 11, Issue 14 pp 5192—5205

Down-regulation of lncRNA MALAT1 alleviates vascular lesion and vascular remodeling of rats with hypertension

Figure 4. Down-regulated MALAT1 and inhibited Notch-1 repress inflammation-related factors expression in rats with HTN. (A) comparison of TNF-α levels in serum of rats; (B) comparison of IL-1β levels in serum of rats; (C) comparison of IL-6 levels in serum of rats; (D) comparison of MCP-1 levels in serum of rats; * P < 0.05 vs the Con group; # P < 0.05 vs the AngII + si-Con group; & P < 0.05 vs the AngII + DMSO group; n = 10, data were expressed as mean ± standard deviation; one-way ANOVA was used for analyzing data, pairwise comparison was analyzed by Tukey’s post hoc test.