Research Paper Volume 11, Issue 19 pp 8139—8155

Hypermethylated long noncoding RNA MEG3 promotes the progression of gastric cancer

Figure 5. Overexpression of MEG3 in vivo inhibits tumor growth. (AC) Tumor xenograft results showed that tumor weight and volume were decreased in the MEG3 group compared with the Con group. *P<0.05, **P<0.01, compared with Con group. (D) QRT-PCR results illustrated that ATP4B expression decreased while miR-181a-5p expression increased in the MEG3 group compared with the Con group. (E) Western blotting results illustrated that ATP4B expression increased in the MEG3 group compared with the Con group. *P<0.05, **P<0.01, compared with Con group.