Research Paper Volume 11, Issue 19 pp 8204—8216

SNHG22 overexpression indicates poor prognosis and induces chemotherapy resistance via the miR-2467/Gal-1 signaling pathway in epithelial ovarian carcinoma

Figure 1. The upregulation of SNHG22 predicts poor outcome in EOC patients. (A) Expression levels of SNHG22 in 90 cases of EOC patient tissues and 20 cases of normal ovarian tissues. (B) Ninety patients were divided into ≤5 cm and >5 cm size groups. The diagram shows SNHG22 expression in each group. (C) Ninety patients were divided into ≤200 U/mL and >200 U/mL CA125 groups. The diagram shows SNHG22 expression in each group. (D and E) Kaplan-Meier analysis of overall survival and recurrence in 90 patients with EOC according to SNHG22 expression (log-rank test). Data are presented as the means ± SDs in three independent experiments. **P < 0.01, ***P < 0.001.