Research Paper Volume 11, Issue 19 pp 8239—8253

The long non-coding RNA, urothelial carcinoma associated 1, promotes cell growth, invasion, migration, and chemo-resistance in glioma through Wnt/β-catenin signaling pathway

Figure 1. UCA1 was up-regulated in glioma cell lines. (A) The expression of UCA1 in human astrocytes and glioma cell lines was determined by qRT-PCR. UCA1 was up-regulated in glioma cell lines (SGH44, U251, U87 and SHG139). The expression of UCA1 in (B) U87 cells and (C) SHG139 cells after UCA1 siRNAs (siUCA1(a) and siUCA1(b)) or scrambled siRNA transfection was determined by qRT-PCR. All the experiments were performed in triplicates. Significant differences compared to the control group were expressed as *P<0.05, **P<0.01 and ***P<0.001.