Research Paper Volume 11, Issue 19 pp 8239—8253

The long non-coding RNA, urothelial carcinoma associated 1, promotes cell growth, invasion, migration, and chemo-resistance in glioma through Wnt/β-catenin signaling pathway

Figure 3. Knock-down of UCA1 inhibited cell invasion and migration in glioma cells. The cell invasive potential in (A) U87 and (B) SHG139 cells after UCA1 siRNAs (siUCA1(a) and siUCA1(b)) or scrambled siRNA transfection was determined by cell invasion assay. The cell migratory potential in (C) U87 and (D) SHG139 cells after UCA1 siRNAs (siUCA1(a) and siUCA1(b)) or scrambled siRNA transfection were assessed by cell migration assay. 1, scrambled siRNA; 2, siUCA1(a); 3, siUCA1(b). All the experiments were performed in triplicates. Significant differences compared to the control group were expressed as *P<0.05 and **P<0.01.