Research Paper Volume 11, Issue 19 pp 8239—8253

The long non-coding RNA, urothelial carcinoma associated 1, promotes cell growth, invasion, migration, and chemo-resistance in glioma through Wnt/β-catenin signaling pathway

Figure 7. UCA1 promoted in vivo tumor growth in the nude mice. (A) The tumor growth of U87 cells with UCA1 overexpression or control U87 cells were assessed in the nude mice. Right panel showed the dissected tumors from the nude mice. (B) Tumor weight was determined in the isolated tumors from the nude mice. (C) The relative expression of UCA1 was determined by qRT-PCR in the isolated tumor tissues from control group and UCA1-overexpresssing group. (D) The relative mRNA expression of axin, β-catenin and cyclin D1 was determined by qRT-PCR in the isolated tumor tissues from control group and UCA1-overexpressing group. N = 5; significant differences compared to the control group were expressed as *P<0.05, **P<0.01 and ***P<0.001.