Research Paper Volume 11, Issue 19 pp 8270—8293

Systematic profiling of alternative splicing events and splicing factors in left- and right-sided colon cancer

Figure 9. Correlation network of DESFs and DEAS events. (A) Correlation network. The correlations between the mRNA levels of the 10 DESFs and the PSI values of each DEAS events were analyzed, and a splicing regulatory network was built among the significant correlations. Quadrate nodes indicate SFs that were upregulated in right-sided (red nodes) or left-sided colon cancer (green nodes). Circular nodes indicate AS that were upregulated in right-sided (red nodes) or left-sided colon cancer (green nodes). Orange lines indicate positive correlations, while deep pink lines indicate negative correlations. (B) Representative dot plots of correlations between the mRNA levels of DESFs and the PSI values of DEAS (P<0.05).