Research Paper Volume 11, Issue 19 pp 8542—8555

Probucol, a “non-statin” cholesterol-lowering drug, ameliorates D-galactose induced cognitive deficits by alleviating oxidative stress via Keap1/Nrf2 signaling pathway in mice

Figure 4. Effect of Prob on ROS and MDA level, and the activities of SOD and GSH-PX. (AC) MDA level and the activities of SOD and GSH-PX in plasma, respectively. (DG) Level of ROS and MDA, and the activities of SOD and GSH-PX in plasma, respectively. Data in each experiment represent mean ± SEM from 10 independent samples. Statistically significant differences were calculated by one-way ANOVA using the SPSS 20.0 software. *P<0.05 and ** P<0.01, versus D-gal group.