Research Paper Volume 11, Issue 23 pp 10796—10813

IL-10 produces a dual effect on OGD-induced neuronal apoptosis of cultured cortical neurons via the NF-κB pathway

Figure 1. OGD-induced peaks of p65 and c-Rel at different time points in cultured primary cortical neurons after OGD injury. (A) The representative image of western blot analysis for p65 and c-Rel. (B) Western blot analysis of p65 (n=3). *p<0.001, as compared with Control group; #p<0.001, as compared with OGD/R3h group; **p<0.001, as compared with OGD/R3h group; ##p<0.001, as compared with OGD/R3h group; ***p<0.001, as compared with OGD/R3h group; ###p<0.001, as compared with OGD/R3h group; by one way analysis of variance (ANOVA) followed by Student-Newman-Keuls multiple comparisons test, F=61.131, p<0.0001. (C) Western blot analysis of c-Rel (n=3). *p>0.05, as compared with Control group; #p<0.001, as compared with OGD/R24h group; **p<0.001, as compared with OGD/R24h group; ##p<0.001, as compared with OGD/R24h group; ***p<0.001, as compared with OGD/R24h group; ###p<0.001, as compared with OGD/R24h group; by one way analysis of variance (ANOVA) followed by Student-Newman-Keuls multiple comparisons test, F=78.545, p<0.0001.