Research Paper Volume 11, Issue 22 pp 10468—10484

Genome-wide association study of hippocampal atrophy rate in non-demented elders

Figure 1. Manhattan and regional plots for associations with hippocampal atrophy rate. (A) Genome-wide signal intensity (Manhattan) plots showing the -log10 (p value) for individual single nucleotide polymorphisms. (B) Regional association results for the 45.0 Mb to 45.8 Mb region of chromosome 19. (C) Association results for the 45.0 Mb to 45.8 Mb region of chromosome 19 controlling for rs4420638. (D) Association results for the 45.0 Mb to 45.8 Mb region of chromosome 19 controlling for rs157582.