Research Paper Volume 11, Issue 22 pp 10468—10484

Genome-wide association study of hippocampal atrophy rate in non-demented elders

Figure 3. Impact of rs4420638 and rs157582 on longitudinal measurements in cognitive scores and brain structures. Associations of rs4420638 with longitudinal measurements in Mini-mental State Examination (MMSE) score (A), Alzheimer Disease Assessment Scale-cognitive subscale 11 (ADAS-cog 11) score (B), entorhinal volume (C) and ventricular volume (D) over time. Associations of rs157582 with longitudinal measurements in MMSE score (E), ADAS-cog 11 score (F), entorhinal volume (G) and ventricular volume (H) over time.