Research Paper Volume 11, Issue 23 pp 10902—10922

The long non-coding RNA SNHG12 promotes gastric cancer by activating the phosphatidylinositol 3-kinase/AKT pathway

Figure 3. SNHG12 promotes the migration and invasion of GC cells. (A, B) Wound healing and Transwell migration assays were performed to evaluate the migration abilities of AGS and MGC-803 cells transfected with si-SNHG12, and of BGC-823 cells transfected with pc-SNHG12. (C) A Transwell invasion assay was conducted to estimate the invasion abilities of AGS and MGC-803 cells transfected with si-SNHG12, and of BGC-823 cells transfected with pc-SNHG12. The migratory and invasive cells were stained with Hoechst. Data are shown as the mean ± SEM of at least three experiments. *P<0.05, **P<0.01, ***P<0.001.