Research Paper Volume 11, Issue 23 pp 11010—11029

Reactive oxygen species metabolism-based prediction model and drug for patients with recurrent glioblastoma

Figure 4. The relationship between recurrence score and tumor immune functions of GBM. (A, B) Correlation matrix of recurrence score and tumor immune functions in the TCGA and CGGA databases. The numbers were the R value of the Pearson correlation analysis. GO1: Immune response. GO2: B cell activation involved in immune response. GO3: T cell activation involved in immune response. GO4: Cytokine production involved in immune response. GO5: Cytokine secretion involved in immune response. GO6: Immune response to tumor cell. GO7: Leukocyte activation involved in immune response. GO8: Natural killer cell-mediated immune response to tumor cell. GO9: T cell-mediated immune response to tumor cell. GO10: Natural killer cell activation involved in immune response. GO11: Myeloid cell activation involved in immune response. (C, D) Correlation matrix of recurrence score and immune checkpoints in TCGA and CGGA databases. Red strips represent positive correlations and green strips represent negative correlations. The wider the strip, the stronger the correlation. The p-value of the correlation analysis between recurrence score and tumor immune functions was provided in Supplementary Table 2.