Research Paper Volume 11, Issue 24 pp 12375—12411

Discovering master regulators in hepatocellular carcinoma: one novel MR, SEC14L2 inhibits cancer cells

Figure 2. MRA agreement among different cohorts using filtered networks. (A) Networks were filtered by applying a DPI threshold of 0.01 to remove the weakest interactions. The scatter plots show ranking agreement (by enrichment P-value) for all regulons. (B) UpSet plot of the intersection of identified regulons in different cohorts. (C) Network visualization of the 120 MRs. The size of circles represents the size of each regulon.