Research Paper Volume 12, Issue 1 pp 70—79

MACC1-AS1 promotes hepatocellular carcinoma cell invasion and proliferation by regulating PAX8

Figure 3. Ectopic expression of MACC1-AS1 induced HCC cell growth. (A) MACC1-AS1 expression was detected in the SMMC7721 cell by using qRT-PCR analysis. (B) MACC1-AS1 expression was detected in the MHCC-97H cell by using qRT-PCR analysis. (C) Ectopic MACC1-AS1 expression promoted cell proliferation in SMMC7721 cell. (D) Overexpression of MACC1-AS1 induced MHCC-97H cell growth. (E) Elevated MACC1-AS1 expression induced the cyclin D1 expression in SMMC7721 cell. (F) The expression of cyclin D1 was analyzed by using qRT-PCR. *p<0.05, **p<0.01 and ***p<0.001.