Research Paper Volume 12, Issue 1 pp 122—137

PRDX5 as a novel binding partner in Nrf2-mediated NSCLC progression under oxidative stress

Figure 4. The effects of Nrf2 and/or PRDX5 shRNA on cell proliferation by EdU incorporation assay. (A) Nrf2 and/or PRDX5 shRNA significantly decreased cell proliferation ratio of A549 cells treated with H2O2 (*P < 0.05). (B) Nrf2 and/or PRDX5 shRNA significantly decreased cell proliferation of NCI-H1299 cells treated with H2O2 (*P < 0.05).