Research Paper Volume 12, Issue 1 pp 204—223

The correlation and role analysis of COL4A1 and COL4A2 in hepatocarcinogenesis

Figure 2. Relationship between the mRNA levels of COL4A1/2 and the clinic pathological features of patients with HCC, stratified based on ethnicity, gender, age, tumor grade, and disease stages (UALCAN). (A, G) Box plot showing the relative transcript level of COL4A1 and COL4A2 in normal and primary tumor (HCC) tissues. (B, H) Box plot showing the relative transcript level of COL4A1 and COL4A2 in normal samples of any ethnicity, and HCC tissues of Caucasian, African-American or Asian. (C, I) Box plot showing the relative transcript level of COL4A1 and COL4A2 in normal tissues of any gender, and HCC tissues of male or female. (D, J) Box plot showing the relative transcript level of COL4A1 and COL4A2 in healthy individuals of any age, and HCC tissues of 21–40, 41–60, 61–80, or 81–100 yrs. (E, K) Box plot showing the relative transcript level of COL4A1 and COL4A2 in normal tissues, and HCC tissues with grade 1, 2, 3 or 4. (F, L) Box plot showing the relative transcript level of COL4A1 and COL4A2 in normal tissues, and HCC tissues in stage 1, 2, 3 or 4. Data are mean ± SE. *, P < 0.05; **, P < 0.01; ***, P < 0.001, ****, P < 0.0001 (t-test).