Research Paper Volume 12, Issue 1 pp 260—287

CircNF1-419 improves the gut microbiome structure and function in AD-like mice

Figure 4. CircNF1-419 changes the gut microbiota genetic trajectory in newborn KM mice. (A) Intestinal physiology changes after infection of over-expressing circNF1-419 AAV. (B) Heatmap of gut microbiota in fimo at phylum level after infection of over-expressing circNF1-419 AAV in young mice. (C) Heatmap of gut microbiota infimo at genus level after infection of over-expressing circNF1-419 AAV in young mice. Data are presented as the means ± SD of more than 8 independent experiments. *p <0.05 and **p <0.01 vs. the model group by one-way ANOVA, followed by the Holm-Sidak test.