Research Paper Volume 12, Issue 1 pp 866—883

Prognostic value of epithelial-mesenchymal transition markers in clear cell renal cell carcinoma

Figure 3. Kaplan Meier survival plot of ccRCC patients in FUSCC cohort according to high and low mRNA expression of six EMT related genes. Lower CDH1 mRNA expression was associated with both worse progression-free survival (p=0.016) and worse overall survival (p<0.001) of ccRCC patients (A, G); CDH2 mRNA expression was not an indicator of either progression-free survival (p=0.288) or overall survival (p=0.202) of ccRCC patients (B, H); Higher SNAI1 mRNA expression was associated with both worse progression-free survival (p<0.001) and worse overall survival (p<0.001) of ccRCC patients (C, I); Higher SNAI2 mRNA expression was associated with both worse progression-free survival (p=0.005) and worse overall survival (p<0.001) of ccRCC patients (D, J); Higher VIM mRNA expression was associated with both worse progression-free survival (p<0.001) and worse overall survival (p<0.001) of ccRCC patients (E, K); Higher TWIST1 mRNA expression was associated with both worse progression-free survival (p<0.001) and worse overall survival (p<0.001) of ccRCC patients (F, L).