Research Paper Volume 12, Issue 3 pp 2246—2260

The protein tyrosine kinase inhibitor, Genistein, delays intervertebral disc degeneration in rats by inhibiting the p38 pathway-mediated inflammatory response

Figure 6. Genistein suppresses the degeneration of NPCs in vivo. (A) MRI images of the caudal intervertebral discs in rats. (B) Thompson score of caudal MRI images from rats after surgery and injection with Genistein. (C) HE staining of intervertebral disc sections from rats after surgery and injection with Genistein. Black scale bar represents 1 mm. (D) Histology score of intervertebral disc sections.