Research Paper Volume 12, Issue 3 pp 2246—2260

The protein tyrosine kinase inhibitor, Genistein, delays intervertebral disc degeneration in rats by inhibiting the p38 pathway-mediated inflammatory response

class="figure-viewer-img"

Figure 7. Genistein attenuates the degeneration and inflammation of NPCs in vivo. (A) COL2A expression in intervertebral disc sections from rats after surgery and injection with Genistein. *p<0.05 (B) p38 expression in intervertebral disc sections from rats after surgery and injection with Genistein. *p<0.05 (C) Optical density quantification of COL2A. Blue scale bar represents 100 μm. (D) Optical density quantification of p38. Blue scale bar represents 100 μm.