Figure 6. Ligustilide reduces oxidative stress in the brains of SAMP8 mice. The supernatant from the hippocampus homogenate was used to assay (A) the MDA level, (B) activities of SOD and (C) the activities of Glutathione peroxidase (GSH-PX). Ligustilide 10 (10 mg/kg/d); Ligustilide 20 (20 mg/kg/d). Data represent mean ± SD (n = 20 per group). #p < 0.05, ##p < 0.01, ###p < 0.001 versus SAMR1; *p < 0.05, **p < 0.01, ***p < 0.001 versus SAMP8.