Research Paper Volume 12, Issue 4 pp 3175—3189

Ligustilide improves aging-induced memory deficit by regulating mitochondrial related inflammation in SAMP8 mice

Figure 8. Ligustilide protects against neuronal apoptosis in hippocampus. (A) The levels of (B) Bax, (C) Bcl-2 and (D) Cleaved caspase-3 were detected in the hippocampus. Ligustilide 10 (10 mg/kg/d); Ligustilide 20 (20 mg/kg/d). Data represent mean ± SD (n = 20 per group). #p < 0.05, ##p < 0.01, ###p < 0.001 versus SAMR1; *p < 0.05, **p < 0.01, ***p < 0.001 versus SAMP8.