Research Paper Volume 12, Issue 4 pp 3175—3189

Ligustilide improves aging-induced memory deficit by regulating mitochondrial related inflammation in SAMP8 mice

Figure 9. Schematic representation of ligustilide improves aging-induced memory deficit by regulating mitochondrial-related dysfunction in SAMP8 mice. Ligustilide improves aging-induced cognitive dysfunction in SAMP8 mice. Ligustilide ameliorates mitochondrial dysfunction in hippocampal neurons, reduces levels of oxidative stress and inflammation, reduces apoptosis in hippocampal neurons.