Research Paper Volume 12, Issue 4 pp 3662—3681

Induction of apoptosis and ferroptosis by a tumor suppressing magnetic field through ROS-mediated DNA damage

Figure 2. MF exposure sensitized tumor cells to chemotherapy. (A, B) G401 cells were treated by 5-fluorouracil (5-FU, 1.5 μM) or by vincristine (VCR, 2 nM) for 3 days, with or without daily MF exposure for 2 h. (C, D) A549 cells were treated by cisplatin (DDP, 2.5 μM) or by paclitaxel (PTX, 0.5 nM) for 3 days, with or without daily MF exposure for 2 h. Inhibition rates were calculated based on cell viability assays. Results are expressed as mean ± SD (n=5). *: P<0.05; **: P<0.01; ***: P<0.001, compared with sham exposure group; #: P<0.05; ##: P<0.01; ###: P<0.001, compared with the chemotherapy group.