Research Paper Volume 12, Issue 4 pp 3682—3693

Exosomes isolated from the plasma of remote ischemic conditioning rats improved cardiac function and angiogenesis after myocardial infarction through targeting Hsp70

Figure 1. RIC remarkably promoted cardiac remodeling and angiogenesis after myocardial infarction. (A) Histopathological analysis of heart tissues by HE, Masson, vWF IHC staining, respectively (scale bar= 100 μm); (B) RIC treatment significantly decreased the infarction ratio; (C) RIC treatment significantly increased left ventricular ejection fraction; (D) RIC treatment significantly increased left ventricular fractional shortening. Data were shown as the mean ± SD (n = 5/each group), * P<0.05 compared with the group MI.