Research Paper Volume 12, Issue 4 pp 3791—3806

Baicalin ameliorates neuropathology in repeated cerebral ischemia-reperfusion injury model mice by remodeling the gut microbiota

Figure 2. Repeated cerebral ischemia-reperfusion in mice increases plasma TMAO levels. (A) LC/MS analysis of plasma TMAO levels in the control and repeated cerebral ischemia-reperfusion model group mice are shown. (B) Spearman analysis shows the association between plasma TMAO levels and the behavioral profile of control and repeated cerebral ischemia-reperfusion model group mice. Note: ** denotes P<0.01 and *** denotes P<0.001 when compared with the control mice using one-way ANOVA analysis followed by Dunnett`s post hoc test. All the values are expressed as means ± S.D. Each group had 15 mice (n=15).