Research Paper Volume 12, Issue 4 pp 3950—3961

Advanced maternal age alters expression of maternal effect genes that are essential for human oocyte quality

Figure 3. GO, KEGG and PPI analysis of DEGs. (A) The top 20 GO terms were presented in the enrichment analyses of DEGs within the older oocytes. (B) The top 20 KEGG pathways were presented in the enrichment analyses of DEGs within the older oocytes. (C) Using the STRING online database, a total of 181 DEGs were filtered into the DEGs PPI network complex. The red box encloses a gene with more than 10 proteins interacting with the protein. (D) PPI subnetworks of TOP2B.