Research Paper Volume 12, Issue 5 pp 4474—4488

Irisin activates Opa1-induced mitophagy to protect cardiomyocytes against apoptosis following myocardial infarction

Figure 3. Irisin activates Opa1-induced mitophagy to restore mitochondrial energy metabolism. (A) Measurement of ATP production by ELISA. (BD) Measurement of mitochondrial respiratory complex activity by ELISA. *P < 0.05 vs. the control group; #P < 0.05 vs. the hypoxia + irisin group.