Priority Research Paper Volume 12, Issue 5 pp 4052—4066

Survey of senescent cell markers with age in human tissues

Figure 9. Muscle. IHC analysis to detect cells expressing p16 (A) or p21 (B) in skeletal muscle of Young, Middle-aged, and Old donors. IHC analysis to detect cells expressing p16 (C) or p21 (D) in cardiac muscle of Young, Middle-aged, and Old donors. These proteins were undetectable in these muscle biopsies (5 cores per organ and age group).