Research Paper Volume 12, Issue 9 pp 7801—7817

Age-related shifts in gut microbiota contribute to cognitive decline in aged rats

Figure 3. Inflammatory cytokines and oxidative stress markers in serum and brain of young and aged rats. n = 6. Serum levels of IL-1β (A), TNF-α (B), and IL-6 (C) in young and aged rats. Expression of IL-1β (D), TNF-α (E), and IL-6 (F) in mPFC and hippocampus in young and aged rats. SOD activity (G), GSH-PX activity (H), and MDA content (I) in serum of young and aged rats. SOD activity (J), GSH-PX activity (K), and MDA content (L) in mPFC and hippocampus of young and aged rats. Error bars represent the SEM. * P < 0.05, ** P < 0.01.