Research Paper Volume 12, Issue 9 pp 7963—7984

Metabolic switching is impaired by aging and facilitated by ketosis independent of glycogen

Figure 4. Aged rats have impaired metabolic parameters when fed ad libitum. Aged rats had significantly elevated (A) insulin, (B) leptin, (C) C-peptide and (D) HOMA levels relative to young rats when fed standard rodent chow ad libitum. Data are represented as group mean ± 1 SEM. * = p < 0.05. For panel A: ad libitum n = 15 young, n = 18 aged. For panel B: n = 27 young, n = 24 aged. For panel C: n = 27 young, n = 23 aged. For panel D: n = 9 young, n = 13 aged.