Research Paper Volume 12, Issue 9 pp 8289—8300

Pluronic P123 modified nano micelles loaded with doxorubicin enhanced tumor-suppressing effect on drug-resistant breast cancer cells

Figure 7. P123-PEG2000-DSPE (Dox) exhibited better anti-tumor effect of on drug-resistant BC mice. (A) The body weights of mice with different treatments, including saline solution (control), Dox, PEG2000-DSPE (Dox), and P123-PEG2000-DSPE (Dox), respectively, every three days for 18 days. (B) The tumor volumes of mice with different treatments, including saline solution (control), Dox, PEG2000-DSPE (Dox), and P123-PEG2000-DSPE (Dox), respectively, every three days for 18 days. (C) The tumor weights of mice with different treatments, including saline solution (control), Dox, PEG2000-DSPE (Dox), and P123-PEG2000-DSPE (Dox), respectively, on 18 days. ***P < 0.001