Research Paper Volume 12, Issue 9 pp 8549—8564

Exosomal miRNA-34 from cancer-associated fibroblasts inhibits growth and invasion of gastric cancer cells in vitro and in vivo

Figure 8. Exosomal miRNA-34 promotes apoptosis of GC cells in vivo. (A) Immunostaining assay for Ki67 in xenograft tumors treated with exosomes loaded with miRNA-34 mimics. (B) Immunostaining assay for cleaved-caspase-3 in xenograft tumors treated with exosomes loaded with miRNA-34 mimics. Values are means ± SD; **, P < 0.01, ***, P < 0.001.