Research Paper Volume 12, Issue 10 pp 9066—9084

Overexpression of miR-142-5p inhibits the progression of nonalcoholic steatohepatitis by targeting TSLP and inhibiting JAK-STAT signaling pathway

Figure 4. The expression of inflammatory factors and JAK-STAT signaling pathway biomarkers in the NASH mouse model. (A) The mRNA expression level of tumor necrosis factor (TNF)-α. (B) The mRNA expression level of interferon (IFN)-β. (C) The mRNA expression level of liver monocyte chemoattractant protein-1 (MCP1). (D) The mRNA expression level of IL-4. (E) The mRNA expression level of IL-6. (F) The expression level of TG in the liver. (G) The protein expression of the biomarkers of JAK-STAT signaling pathway. All data were means ± SD. *P < 0.05, compared with WT group; #P < 0.05, compared with NC group; ^P < 0.05, compared with A142 group.